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The Hsp90 Co-Chaperone Sgt1 Governs Candida albicans Morphogenesis and Drug Resistance

The molecular chaperone Hsp90 orchestrates regulatory circuitry governing fungal morphogenesis, biofilm development, drug resistance, and virulence. Hsp90 functions in concert with co-chaperones to regulate stability and activation of client proteins, many of which are signal transducers. Here, we c...

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Bibliographic Details
Main Authors: Shapiro, Rebecca S., Zaas, Aimee K., Betancourt-Quiroz, Marisol, Perfect, John R., Cowen, Leah E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435277/
https://ncbi.nlm.nih.gov/pubmed/22970302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044734
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