Hsp90 Governs Echinocandin Resistance in the Pathogenic Yeast Candida albicans via Calcineurin

Candida albicans is the leading fungal pathogen of humans, causing life-threatening disease in immunocompromised individuals. Treatment of candidiasis is hampered by the limited number of antifungal drugs whose efficacy is compromised by host toxicity, fungistatic activity, and the emergence of drug...

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Bibliographic Details
Main Authors: Singh, Sheena D., Robbins, Nicole, Zaas, Aimee K., Schell, Wiley A., Perfect, John R., Cowen, Leah E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712069/
https://ncbi.nlm.nih.gov/pubmed/19649312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000532
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