Structure of a modular polyketide synthase

Polyketide natural products constitute a broad class of compounds with diverse structural features and biological activities. Their biosynthetic machinery, represented by type I polyketide synthases, has an architecture in which successive modules catalyze two-carbon linear extensions and keto group...

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Publicado en:Nature
Main Authors: Dutta, Somnath, Whicher, Jonathan R., Hansen, Douglas A., Hale, Wendi A., Chemler, Joseph A., Congdon, Grady R., Narayan, Alison R., Håkansson, Kristina, Sherman, David H., Smith, Janet L., Skiniotis, Georgios
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278352/
https://ncbi.nlm.nih.gov/pubmed/24965652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13423
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