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The code for directing proteins for translocation across ER membrane: SRP cotranslationally recognizes specific features of a signal sequence

The signal recognition particle (SRP) cotranslationally recognizes signal sequences of secretory proteins and targets ribosome-nascent chain complexes (RNCs) to the SRP receptor in the endoplasmic reticulum membrane, initiating translocation of the nascent chain through the Sec61 translocon. Althoug...

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Bibliografiske detaljer
Udgivet i:J Mol Biol
Main Authors: Nilsson, IngMarie, Lara, Patricia, Hessa, Tara, Johnson, Arthur E., von Heijne, Gunnar, Karamyshev, Andrey L.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277940/
https://ncbi.nlm.nih.gov/pubmed/24979680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.06.014
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