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The code for directing proteins for translocation across ER membrane: SRP cotranslationally recognizes specific features of a signal sequence
The signal recognition particle (SRP) cotranslationally recognizes signal sequences of secretory proteins and targets ribosome-nascent chain complexes (RNCs) to the SRP receptor in the endoplasmic reticulum membrane, initiating translocation of the nascent chain through the Sec61 translocon. Althoug...
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| Udgivet i: | J Mol Biol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4277940/ https://ncbi.nlm.nih.gov/pubmed/24979680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.06.014 |
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