Role of Hypoxia Inducing Factor-1β in Alcohol-Induced Autophagy, Steatosis and Liver Injury in Mice

Chronic alcohol causes liver hypoxia and steatosis, which eventually develops into alcoholic liver disease (ALD). While it has been known that alcohol consumption activates hepatic hypoxia inducing factor-1α (HIF-1α), conflicting results regarding the role of HIF-1α in alcohol-induced liver injury a...

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Udgivet i:PLoS One
Main Authors: Ni, Hong-Min, Bhakta, Amar, Wang, Shaogui, Li, Zhenrui, Manley, Sharon, Huang, Heqing, Copple, Bryan, Ding, Wen-Xing
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275262/
https://ncbi.nlm.nih.gov/pubmed/25536043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115849
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