Role of Hypoxia Inducing Factor-1β in Alcohol-Induced Autophagy, Steatosis and Liver Injury in Mice

Chronic alcohol causes liver hypoxia and steatosis, which eventually develops into alcoholic liver disease (ALD). While it has been known that alcohol consumption activates hepatic hypoxia inducing factor-1α (HIF-1α), conflicting results regarding the role of HIF-1α in alcohol-induced liver injury a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ni, Hong-Min, Bhakta, Amar, Wang, Shaogui, Li, Zhenrui, Manley, Sharon, Huang, Heqing, Copple, Bryan, Ding, Wen-Xing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275262/
https://ncbi.nlm.nih.gov/pubmed/25536043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115849
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