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Role of Mechanistic Target of Rapamycin and Autophagy in Alcohol-Induced Adipose Atrophy and Liver Injury

Chronic alcohol consumption induces adipose tissue atrophy. However, the mechanisms for how alcohol induces lipodystrophy and its impact on liver steatosis and injury are not fully elucidated. Autophagy is a highly conserved lysosomal degradation pathway, which regulates cellular homeostasis. Mice w...

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Détails bibliographiques
Publié dans:Am J Pathol
Auteurs principaux: Li, Yuan, Chao, Xiaojuan, Wang, Shaogui, Williams, Jessica A., Ni, Hong-Min, Ding, Wen-Xing
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940593/
https://ncbi.nlm.nih.gov/pubmed/31733185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.09.023
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