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Role of Mechanistic Target of Rapamycin and Autophagy in Alcohol-Induced Adipose Atrophy and Liver Injury

Chronic alcohol consumption induces adipose tissue atrophy. However, the mechanisms for how alcohol induces lipodystrophy and its impact on liver steatosis and injury are not fully elucidated. Autophagy is a highly conserved lysosomal degradation pathway, which regulates cellular homeostasis. Mice w...

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Vydáno v:Am J Pathol
Hlavní autoři: Li, Yuan, Chao, Xiaojuan, Wang, Shaogui, Williams, Jessica A., Ni, Hong-Min, Ding, Wen-Xing
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940593/
https://ncbi.nlm.nih.gov/pubmed/31733185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.09.023
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