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Role of Mechanistic Target of Rapamycin and Autophagy in Alcohol-Induced Adipose Atrophy and Liver Injury

Chronic alcohol consumption induces adipose tissue atrophy. However, the mechanisms for how alcohol induces lipodystrophy and its impact on liver steatosis and injury are not fully elucidated. Autophagy is a highly conserved lysosomal degradation pathway, which regulates cellular homeostasis. Mice w...

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Bibliografiske detaljer
Udgivet i:Am J Pathol
Main Authors: Li, Yuan, Chao, Xiaojuan, Wang, Shaogui, Williams, Jessica A., Ni, Hong-Min, Ding, Wen-Xing
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940593/
https://ncbi.nlm.nih.gov/pubmed/31733185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.09.023
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