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Role of Mechanistic Target of Rapamycin and Autophagy in Alcohol-Induced Adipose Atrophy and Liver Injury

Chronic alcohol consumption induces adipose tissue atrophy. However, the mechanisms for how alcohol induces lipodystrophy and its impact on liver steatosis and injury are not fully elucidated. Autophagy is a highly conserved lysosomal degradation pathway, which regulates cellular homeostasis. Mice w...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Pathol
Hauptverfasser: Li, Yuan, Chao, Xiaojuan, Wang, Shaogui, Williams, Jessica A., Ni, Hong-Min, Ding, Wen-Xing
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940593/
https://ncbi.nlm.nih.gov/pubmed/31733185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.09.023
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