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Role of Hypoxia Inducing Factor-1β in Alcohol-Induced Autophagy, Steatosis and Liver Injury in Mice

Chronic alcohol causes liver hypoxia and steatosis, which eventually develops into alcoholic liver disease (ALD). While it has been known that alcohol consumption activates hepatic hypoxia inducing factor-1α (HIF-1α), conflicting results regarding the role of HIF-1α in alcohol-induced liver injury a...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Ni, Hong-Min, Bhakta, Amar, Wang, Shaogui, Li, Zhenrui, Manley, Sharon, Huang, Heqing, Copple, Bryan, Ding, Wen-Xing
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275262/
https://ncbi.nlm.nih.gov/pubmed/25536043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115849
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