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Role of tautomerism in RNA biochemistry

Heterocyclic nucleic acid bases and their analogs can adopt multiple tautomeric forms due to the presence of multiple solvent-exchangeable protons. In DNA, spontaneous formation of minor tautomers has been speculated to contribute to mutagenic mispairings during DNA replication, whereas in RNA, mino...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Singh, Vipender, Fedeles, Bogdan I., Essigmann, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274630/
https://ncbi.nlm.nih.gov/pubmed/25516996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.048371.114
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