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Impact of DNA Lesion Repair, Replication and Formation on the Mutational Spectra of Environmental Carcinogens: Aflatoxin B(1) as a Case Study

In a multicellular organism, somatic mutations represent a permanent record of the past chemical and biochemical perturbations experienced by a cell in its local microenvironment. Akin to a perpetual recording device, with every replication, genomic DNA accumulates mutations in patterns that reflect...

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Bibliografiska uppgifter
I publikationen:DNA Repair (Amst)
Huvudupphovsmän: Fedeles, Bogdan I., Essigmann, John M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340726/
https://ncbi.nlm.nih.gov/pubmed/30309820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.08.008
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