Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence

It is widely believed that epidemics in new hosts diminish in virulence over time, with natural selection favoring pathogens that cause minimal disease. However, a tradeoff frequently exists between high virulence shortening host survival on the one hand but allowing faster transmission on the other...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:Proc Natl Acad Sci U S A
Główni autorzy: Payne, Rebecca, Muenchhoff, Maximilian, Mann, Jaclyn, Roberts, Hannah E., Matthews, Philippa, Adland, Emily, Hempenstall, Allison, Huang, Kuan-Hsiang, Brockman, Mark, Brumme, Zabrina, Sinclair, Marc, Miura, Toshiyuki, Frater, John, Essex, Myron, Shapiro, Roger, Walker, Bruce D., Ndung’u, Thumbi, McLean, Angela R., Carlson, Jonathan M., Goulder, Philip J. R.
Format: Artigo
Język:Inglês
Wydane: National Academy of Sciences 2014
Hasła przedmiotowe:
PNAS Plus
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273423/
https://ncbi.nlm.nih.gov/pubmed/25453107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413339111
Etykiety: Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!

Podobne zapisy