Magnesium supplementation and high volume hydration reduce the renal toxicity caused by cisplatin-based chemotherapy in patients with lung cancer: a toxicity study

BACKGROUND: Renal toxicity is a clinical problem that affects 28 − 42% of patients undergoing treatment with cisplatin. Renal toxicity can be minimized by high volume hydration with mannitol diuresis. Recent reports have shown that cisplatin induces depletion of Mg and that Mg supplementation can re...

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Udgivet i:BMC Pharmacol Toxicol
Main Authors: Oka, Takako, Kimura, Tatsuo, Suzumura, Tomohiro, Yoshimoto, Naoki, Nakai, Toshiyuki, Yamamoto, Norio, Matsuura, Kuniomi, Mitsuoka, Shigeki, Yoshimura, Naruo, Kudoh, Shinzoh, Hirata, Kazuto
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272804/
https://ncbi.nlm.nih.gov/pubmed/25472655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-15-70
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