Magnesium supplementation and high volume hydration reduce the renal toxicity caused by cisplatin-based chemotherapy in patients with lung cancer: a toxicity study

BACKGROUND: Renal toxicity is a clinical problem that affects 28 − 42% of patients undergoing treatment with cisplatin. Renal toxicity can be minimized by high volume hydration with mannitol diuresis. Recent reports have shown that cisplatin induces depletion of Mg and that Mg supplementation can re...

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Publicat a:BMC Pharmacol Toxicol
Autors principals: Oka, Takako, Kimura, Tatsuo, Suzumura, Tomohiro, Yoshimoto, Naoki, Nakai, Toshiyuki, Yamamoto, Norio, Matsuura, Kuniomi, Mitsuoka, Shigeki, Yoshimura, Naruo, Kudoh, Shinzoh, Hirata, Kazuto
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272804/
https://ncbi.nlm.nih.gov/pubmed/25472655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-15-70
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