Magnesium supplementation and high volume hydration reduce the renal toxicity caused by cisplatin-based chemotherapy in patients with lung cancer: a toxicity study

BACKGROUND: Renal toxicity is a clinical problem that affects 28 − 42% of patients undergoing treatment with cisplatin. Renal toxicity can be minimized by high volume hydration with mannitol diuresis. Recent reports have shown that cisplatin induces depletion of Mg and that Mg supplementation can re...

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Detalhes bibliográficos
Publicado no:BMC Pharmacol Toxicol
Main Authors: Oka, Takako, Kimura, Tatsuo, Suzumura, Tomohiro, Yoshimoto, Naoki, Nakai, Toshiyuki, Yamamoto, Norio, Matsuura, Kuniomi, Mitsuoka, Shigeki, Yoshimura, Naruo, Kudoh, Shinzoh, Hirata, Kazuto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272804/
https://ncbi.nlm.nih.gov/pubmed/25472655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-15-70
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