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Nucleo-cytoplasmic transport as a therapeutic target of cancer

Shuttling of specific proteins out of the nucleus is essential for the regulation of the cell cycle and proliferation of both normal and malignant tissues. Dysregulation of this fundamental process may affect many other important cellular processes such as tumor growth, inflammatory response, cell c...

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Détails bibliographiques
Publié dans:J Hematol Oncol
Auteurs principaux: Gravina, Giovanni Luca, Senapedis, William, McCauley, Dilara, Baloglu, Erkan, Shacham, Sharon, Festuccia, Claudio
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272779/
https://ncbi.nlm.nih.gov/pubmed/25476752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0085-1
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