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FGF signaling specifies hematopoietic stem cells through its regulation of somitic Notch signaling
Hematopoietic stem cells (HSCs) derive from hemogenic endothelial cells of the primitive dorsal aorta (DA) during vertebrate embryogenesis. The molecular mechanisms governing this unique endothelial to hematopoietic transition remain unclear. Here, we demonstrate a novel requirement for fibroblast g...
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| Publicado en: | Nat Commun |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4271318/ https://ncbi.nlm.nih.gov/pubmed/25428693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6583 |
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