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Discrete Notch signaling requirements in the specification of hematopoietic stem cells

Hematopoietic stem cells (HSCs) require multiple molecular inputs for proper specification, including activity of the Notch signaling pathway. A requirement for the Notch1 and dispensability of the Notch2 receptor has been demonstrated in mice, but the role of the remaining Notch receptors has not b...

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Podrobná bibliografie
Vydáno v:EMBO J
Hlavní autoři: Kim, Albert D, Melick, Chase H, Clements, Wilson K, Stachura, David L, Distel, Martin, Panáková, Daniela, MacRae, Calum, Mork, Lindsey A, Crump, J Gage, Traver, David
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253525/
https://ncbi.nlm.nih.gov/pubmed/25230933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488784
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