Discrete Notch signaling requirements in the specification of hematopoietic stem cells

Hematopoietic stem cells (HSCs) require multiple molecular inputs for proper specification, including activity of the Notch signaling pathway. A requirement for the Notch1 and dispensability of the Notch2 receptor has been demonstrated in mice, but the role of the remaining Notch receptors has not b...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Kim, Albert D, Melick, Chase H, Clements, Wilson K, Stachura, David L, Distel, Martin, Panáková, Daniela, MacRae, Calum, Mork, Lindsey A, Crump, J Gage, Traver, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BlackWell Publishing Ltd 2014
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253525/
https://ncbi.nlm.nih.gov/pubmed/25230933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488784
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