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FGF signaling specifies hematopoietic stem cells through its regulation of somitic Notch signaling

Hematopoietic stem cells (HSCs) derive from hemogenic endothelial cells of the primitive dorsal aorta (DA) during vertebrate embryogenesis. The molecular mechanisms governing this unique endothelial to hematopoietic transition remain unclear. Here, we demonstrate a novel requirement for fibroblast g...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Lee, Yoonsung, Manegold, Jennifer E, Kim, Albert D, Pouget, Claire, Stachura, David L, Clements, Wilson K, Traver, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271318/
https://ncbi.nlm.nih.gov/pubmed/25428693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6583
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