FGF signaling restricts hematopoietic stem cell specification via modulation of the BMP pathway

Hematopoietic stem cells (HSCs) are produced during embryogenesis from the floor of the dorsal aorta. The localization of HSCs is dependent upon the presence of instructive signals on the ventral side of the vessel. The nature of the extrinsic molecular signals that control the aortic hematopoietic...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Pouget, Claire, Peterkin, Tessa, Simões, Filipa Costa, Lee, Yoonsung, Traver, David, Patient, Roger
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374634/
https://ncbi.nlm.nih.gov/pubmed/25429520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6588
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