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FGF signaling restricts hematopoietic stem cell specification via modulation of the BMP pathway

Hematopoietic stem cells (HSCs) are produced during embryogenesis from the floor of the dorsal aorta. The localization of HSCs is dependent upon the presence of instructive signals on the ventral side of the vessel. The nature of the extrinsic molecular signals that control the aortic hematopoietic...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Pouget, Claire, Peterkin, Tessa, Simões, Filipa Costa, Lee, Yoonsung, Traver, David, Patient, Roger
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374634/
https://ncbi.nlm.nih.gov/pubmed/25429520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6588
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