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Hedgehog and Bmp polarise haematopoietic stem cell emergence in the zebrafish dorsal aorta
Haematopoietic stem cells (HSCs) are first detected in the floor of the embryonic dorsal aorta (DA) and here we investigate the signals that induce the HSC programme there. We show that while continued Hedgehog (Hh) signalling from the overlying midline structures maintains the arterial programme ch...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210643/ https://ncbi.nlm.nih.gov/pubmed/19531361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.04.014 |
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