Hedgehog and Bmp polarise haematopoietic stem cell emergence in the zebrafish dorsal aorta

Haematopoietic stem cells (HSCs) are first detected in the floor of the embryonic dorsal aorta (DA) and here we investigate the signals that induce the HSC programme there. We show that while continued Hedgehog (Hh) signalling from the overlying midline structures maintains the arterial programme ch...

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Hlavní autoři: Wilkinson, Robert N., Pouget, Claire, Gering, Martin, Russell, Angela J., Davies, Stephen G., Kimelman, David, Patient, Roger
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210643/
https://ncbi.nlm.nih.gov/pubmed/19531361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.04.014
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