Hedgehog and Bmp polarise haematopoietic stem cell emergence in the zebrafish dorsal aorta

Haematopoietic stem cells (HSCs) are first detected in the floor of the embryonic dorsal aorta (DA) and here we investigate the signals that induce the HSC programme there. We show that while continued Hedgehog (Hh) signalling from the overlying midline structures maintains the arterial programme ch...

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Autores principales: Wilkinson, Robert N., Pouget, Claire, Gering, Martin, Russell, Angela J., Davies, Stephen G., Kimelman, David, Patient, Roger
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210643/
https://ncbi.nlm.nih.gov/pubmed/19531361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.04.014
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