Influenza Promotes Collagen Deposition via αvβ6 Integrin-mediated Transforming Growth Factor β Activation

Influenza infection exacerbates chronic pulmonary diseases, including idiopathic pulmonary fibrosis. A central pathway in the pathogenesis of idiopathic pulmonary fibrosis is epithelial injury leading to activation of transforming growth factor β (TGFβ). The mechanism and functional consequences of...

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Vydáno v:J Biol Chem
Hlavní autoři: Jolly, Lisa, Stavrou, Anastasios, Vanderstoken, Gilles, Meliopoulos, Victoria A., Habgood, Anthony, Tatler, Amanda L., Porte, Joanne, Knox, Alan, Weinreb, Paul, Violette, Shelia, Hussell, Tracy, Kolb, Martin, Stampfli, Martin R., Schultz-Cherry, Stacey, Jenkins, Gisli
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271213/
https://ncbi.nlm.nih.gov/pubmed/25339175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.582262
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