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Epigenetic Changes in p21 Expression in Renal Cells after Exposure to Bromate

This study tested the hypothesis that bromate (KBrO(3))-induced renal cell death is mediated by epigenetic mechanisms. Global DNA methylation, as assessed by 5-methylcytosine staining, was not changed in normal rat kidney cells treated with acute cytotoxic doses of KBrO(3) (100 and 200 ppm), as comp...

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Vydáno v:Toxicol Sci
Hlavní autoři: Scholpa, N.E., Zhang, X., Kolli, R.T., Cummings, B.S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
116
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271043/
https://ncbi.nlm.nih.gov/pubmed/25015661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu138
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