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Nephrotoxicity of Epigenetic Inhibitors Used for the Treatment of Cancer

This study determined the anti-neoplastic activity and nephrotoxicity of epigenetic inhibitors in vitro. The therapeutic efficacy of epigenetic inhibitors was determined in human prostate cancer cells (PC-3 and LNCaP) using the DNA methyltransferase inhibitor 5-azacytidine (5-Aza) and the histone de...

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Detalhes bibliográficos
Publicado no:Chem Biol Interact
Main Authors: Scholpa, N.E., Kolli, R.T., Moore, M., Arnold, R.D., Glenn, T.C., Cummings, B.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045804/
https://ncbi.nlm.nih.gov/pubmed/27543423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2016.08.010
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