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Cyclin-Dependent Kinase Inhibitor 1a (p21) Modulates Response to Cocaine and Motivated Behaviors
This study investigated the functional role of cyclin-dependent kinase inhibitor 1a (Cdkn1a or p21) in cocaine-induced responses using a knockout mouse model. Acute locomotor activity after cocaine administration (15 mg/kg, i.p.) was decreased in p21(−/−) mice, whereas cocaine-induced place preferen...
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| Pubblicato in: | J Pharmacol Exp Ther |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4809318/ https://ncbi.nlm.nih.gov/pubmed/26791604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.230888 |
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