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Inhibition of poly (ADP-ribose) polymerase and inducible nitric oxide synthase protects against ischemic myocardial damage by reduction of apoptosis

Myocardial infarction (MI) is defined as the deprivation of the myocardial tissue of oxygen and nutrients, resulting in the induction of inflammation and apoptosis of the cardiomyocytes. Poly (ADP-ribose) polymerase 1 (PARP1) is a nuclear enzyme closely associated with MI, that can be activated by D...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: WANG, JUAN, HAO, LIN, WANG, YAN, QIN, WEIDONG, WANG, XIN, ZHAO, TONG, LIU, YUSHENG, SHENG, LIN, DU, YIMENG, ZHANG, MENGYUAN, LU, QINGHUA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270331/
https://ncbi.nlm.nih.gov/pubmed/25412407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2014.2977
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