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Inhibition of poly (ADP-ribose) polymerase and inducible nitric oxide synthase protects against ischemic myocardial damage by reduction of apoptosis

Myocardial infarction (MI) is defined as the deprivation of the myocardial tissue of oxygen and nutrients, resulting in the induction of inflammation and apoptosis of the cardiomyocytes. Poly (ADP-ribose) polymerase 1 (PARP1) is a nuclear enzyme closely associated with MI, that can be activated by D...

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Publicat a:Mol Med Rep
Autors principals: WANG, JUAN, HAO, LIN, WANG, YAN, QIN, WEIDONG, WANG, XIN, ZHAO, TONG, LIU, YUSHENG, SHENG, LIN, DU, YIMENG, ZHANG, MENGYUAN, LU, QINGHUA
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270331/
https://ncbi.nlm.nih.gov/pubmed/25412407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2014.2977
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