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Epigenetic Function of Activation-Induced Cytidine Deaminase and Its Link to Lymphomagenesis
Activation-induced cytidine deaminase (AID) is essential for somatic hypermutation and class switch recombination of immunoglobulin (Ig) genes during B cell maturation and immune response. Expression of AID is tightly regulated due to its mutagenic and recombinogenic potential, which is known to tar...
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| Pubblicato in: | Front Immunol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4270259/ https://ncbi.nlm.nih.gov/pubmed/25566255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00642 |
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