Activation-induced cytidine deaminase (AID) linking immunity, chronic inflammation, and cancer

Activation-induced cytidine deaminase (AID) is critically involved in class switch recombination and somatic hypermutation of Ig loci resulting in diversification of antibodies repertoire and production of high-affinity antibodies and as such represents a physiological tool to introduce DNA alterati...

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Bibliographic Details
Main Authors: Mechtcheriakova, Diana, Svoboda, Martin, Meshcheryakova, Anastasia, Jensen-Jarolim, Erika
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2012
Subjects:
Symposium-in-Writing Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427704/
https://ncbi.nlm.nih.gov/pubmed/22527246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-012-1255-z
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