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Impact of familial hypertrophic cardiomyopathy-linked mutations in the NH(2) terminus of the RLC on β-myosin cross-bridge mechanics
Familial hypertrophic cardiomyopathy (HCM) is associated with mutations in sarcomeric proteins, including the myosin regulatory light chain (RLC). Here we studied the impact of three HCM mutations located in the NH(2) terminus of the RLC on the molecular mechanism of β-myosin heavy chain (MHC) cross...
में बचाया:
में प्रकाशित: | J Appl Physiol (1985) |
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मुख्य लेखकों: | , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
American Physiological Society
2014
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4269682/ https://ncbi.nlm.nih.gov/pubmed/25324513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00798.2014 |
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