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Enhanced Performance of Plasmid DNA Polyplexes Stabilized by a Combination of Core Hydrophobicity and Surface PEGylation

Nonviral gene therapy has high potential for safely promoting tissue restoration and for treating various genetic diseases. One current limitation is that conventional transfection reagents such as polyethylenimine (PEI) form electrostatically stabilized plasmid DNA (pDNA) polyplexes with poor collo...

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Bibliografiska uppgifter
I publikationen:J Mater Chem B Mater Biol Med
Huvudupphovsmän: Adolph, Elizabeth J., Nelson, Christopher E., Werfel, Thomas A., Guo, Ruijing, Davidson, Jeffrey M., Guelcher, Scott A., Duvall, Craig L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269243/
https://ncbi.nlm.nih.gov/pubmed/25530856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4TB00352G
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