Multimeric Scaffolds Displaying the HIV-1 Envelope MPER Induce MPER-Specific Antibodies and Cross-Neutralizing Antibodies when Co-Immunized with gp160 DNA

Developing a vaccine that overcomes the diversity of HIV-1 is likely to require a strategy that directs antibody (Ab) responses toward conserved regions of the viral Envelope (Env). However, the generation of neutralizing Abs (NAbs) targeting these regions through vaccination has proven to be diffic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Krebs, Shelly J., McBurney, Sean P., Kovarik, Dina N., Waddell, Chelsea D., Jaworski, J. Pablo, Sutton, William F., Gomes, Michelle M., Trovato, Maria, Waagmeester, Garret, Barnett, Susan J., DeBerardinis, Piergiuseppe, Haigwood, Nancy L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267727/
https://ncbi.nlm.nih.gov/pubmed/25514675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113463
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