Multimeric Scaffolds Displaying the HIV-1 Envelope MPER Induce MPER-Specific Antibodies and Cross-Neutralizing Antibodies when Co-Immunized with gp160 DNA

Developing a vaccine that overcomes the diversity of HIV-1 is likely to require a strategy that directs antibody (Ab) responses toward conserved regions of the viral Envelope (Env). However, the generation of neutralizing Abs (NAbs) targeting these regions through vaccination has proven to be diffic...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Krebs, Shelly J., McBurney, Sean P., Kovarik, Dina N., Waddell, Chelsea D., Jaworski, J. Pablo, Sutton, William F., Gomes, Michelle M., Trovato, Maria, Waagmeester, Garret, Barnett, Susan J., DeBerardinis, Piergiuseppe, Haigwood, Nancy L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267727/
https://ncbi.nlm.nih.gov/pubmed/25514675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113463
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