E2 multimeric scaffold for vaccine formulation: immune response by intranasal delivery and transcriptome profile of E2-pulsed dendritic cells

BACKGROUND: The E2 multimeric scaffold represents a powerful delivery system able to elicit robust humoral and cellular immune responses upon systemic administrations. Here recombinant E2 scaffold displaying the third variable loop of HIV-1 Envelope gp120 glycoprotein was administered via mucosa, an...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Trovato, Maria, Maurano, Francesco, D’Apice, Luciana, Costa, Valerio, Sartorius, Rossella, Cuccaro, Fausta, McBurney, Sean P., Krebs, Shelly J., Prisco, Antonella, Ciccodicola, Alfredo, Rossi, Mauro, Haigwood, Nancy L., De Berardinis, Piergiuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947308/
https://ncbi.nlm.nih.gov/pubmed/27421762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-016-0772-x
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