Multimeric Scaffolds Displaying the HIV-1 Envelope MPER Induce MPER-Specific Antibodies and Cross-Neutralizing Antibodies when Co-Immunized with gp160 DNA

Developing a vaccine that overcomes the diversity of HIV-1 is likely to require a strategy that directs antibody (Ab) responses toward conserved regions of the viral Envelope (Env). However, the generation of neutralizing Abs (NAbs) targeting these regions through vaccination has proven to be diffic...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Krebs, Shelly J., McBurney, Sean P., Kovarik, Dina N., Waddell, Chelsea D., Jaworski, J. Pablo, Sutton, William F., Gomes, Michelle M., Trovato, Maria, Waagmeester, Garret, Barnett, Susan J., DeBerardinis, Piergiuseppe, Haigwood, Nancy L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267727/
https://ncbi.nlm.nih.gov/pubmed/25514675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113463
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