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Easy quantitative assessment of genome editing by sequence trace decomposition

The efficacy and the mutation spectrum of genome editing methods can vary substantially depending on the targeted sequence. A simple, quick assay to accurately characterize and quantify the induced mutations is therefore needed. Here we present TIDE, a method for this purpose that requires only a pa...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Brinkman, Eva K., Chen, Tao, Amendola, Mario, van Steensel, Bas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267669/
https://ncbi.nlm.nih.gov/pubmed/25300484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku936
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