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Easy quantitative assessment of genome editing by sequence trace decomposition
The efficacy and the mutation spectrum of genome editing methods can vary substantially depending on the targeted sequence. A simple, quick assay to accurately characterize and quantify the induced mutations is therefore needed. Here we present TIDE, a method for this purpose that requires only a pa...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4267669/ https://ncbi.nlm.nih.gov/pubmed/25300484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku936 |
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