Tespa1 negatively regulates FcεRI-mediated signaling and the mast cell–mediated allergic response

Antigen-mediated cross-linking of IgE on mast cells triggers a signaling cascade that results in their degranulation and proinflammatory cytokine production, which are key effectors in allergic reactions. We show that the activation of mast cells is negatively regulated by the newly identified adapt...

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書誌詳細
出版年:J Exp Med
主要な著者: Wang, Di, Zheng, Mingzhu, Qiu, Yuanjun, Guo, Chuansheng, Ji, Jian, Lei, Lei, Zhang, Xue, Liang, Jingjing, Lou, Jun, Huang, Wei, Dong, Bowen, Wu, Songquan, Wang, Jianli, Ke, Yuehai, Cao, Xuetao, Zhou, Yi Ting, Lu, Linrong
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2014
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267239/
https://ncbi.nlm.nih.gov/pubmed/25422497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20140470
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