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SWAP-70 regulates mast cell FcεRI-mediated signaling and anaphylaxis

Mast cells, perhaps best known by their ability to trigger allergic reactions after stimulation through the FcεRI, express the unusual phosphatidylinositol-3-kinase (PI3K)-dependent, Rac-binding protein SWAP-70. Here we show that the IgE-mediated passive cutaneous and the systemic anaphylactic respo...

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Detalhes bibliográficos
Main Authors: Sivalenka, Raja Rajeswari, Sinha, Manoj, Jessberger, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954288/
https://ncbi.nlm.nih.gov/pubmed/18236401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737597
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