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Sequential Engagement of FcεRI on Mast Cells and Basophil Histamine H(4) Receptor and FcεRI in Allergic Rhinitis
Histamine H(4) receptor (H(4)R)-deficient mice (H(4)R(−/−)), H(4)R antagonist-treated WT mice, and WT mice depleted of basophils failed to develop early (EPR) or late phase (LPR) nasal responses following allergen sensitization and challenge. Basophil transfer from WT but not H(4)R(−/−) mice restore...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538893/ https://ncbi.nlm.nih.gov/pubmed/23241885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202049 |
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