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Oligomerization status influences subcellular deposition and glycosylation of recombinant butyrylcholinesterase in Nicotiana benthamiana

Plants have a proven track record for the expression of biopharmaceutically interesting proteins. Importantly, plants and mammals share a highly conserved secretory pathway that allows similar folding, assembly and posttranslational modifications of proteins. Human butyrylcholinesterase (BChE) is a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Plant Biotechnol J
Hauptverfasser: Schneider, Jeannine D, Marillonnet, Sylvestre, Castilho, Alexandra, Gruber, Clemens, Werner, Stefan, Mach, Lukas, Klimyuk, Victor, Mor, Tsafrir S, Steinkellner, Herta
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265266/
https://ncbi.nlm.nih.gov/pubmed/24618259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.12184
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