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Expression of human butyrylcholinesterase with an engineered glycosylation profile resembling the plasma-derived orthologue
Human butyrylcholinesterase (BChE) is considered a candidate bioscavenger of nerve agents for use in pre- and post-exposure treatment. The presence and functional necessity of complex N-glycans (i.e. sialylated structures) is a challenging issue in respect to its recombinant expression. We aim to pr...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3975692/ https://ncbi.nlm.nih.gov/pubmed/24130173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201300229 |
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