Expression of human butyrylcholinesterase with an engineered glycosylation profile resembling the plasma-derived orthologue

Human butyrylcholinesterase (BChE) is considered a candidate bioscavenger of nerve agents for use in pre- and post-exposure treatment. The presence and functional necessity of complex N-glycans (i.e. sialylated structures) is a challenging issue in respect to its recombinant expression. We aim to pr...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Schneider, Jeannine D., Castilho, Alexandra, Neumann, Laura, Altmann, Friedrich, Loos, Andreas, Kannan, Latha, Mor, Tsafrir S., Steinkellner, Herta
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975692/
https://ncbi.nlm.nih.gov/pubmed/24130173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201300229
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы