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Identification of two subtilisin‐like serine proteases engaged in the degradation of recombinant proteins in Nicotiana benthamiana

The tobacco variant Nicotiana benthamiana has recently emerged as a versatile host for the manufacturing of protein therapeutics, but the fidelity of many recombinant proteins generated in this system is compromised by inadvertent proteolysis. Previous studies have revealed that the anti‐HIV‐1 antib...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Puchol Tarazona, Alejandro A., Maresch, Daniel, Grill, Annette, Bakalarz, Janet, Torres Acosta, Juan A., Castilho, Alexandra, Steinkellner, Herta, Mach, Lukas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221030/
https://ncbi.nlm.nih.gov/pubmed/33263189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.14014
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