Identification of two subtilisin‐like serine proteases engaged in the degradation of recombinant proteins in Nicotiana benthamiana

The tobacco variant Nicotiana benthamiana has recently emerged as a versatile host for the manufacturing of protein therapeutics, but the fidelity of many recombinant proteins generated in this system is compromised by inadvertent proteolysis. Previous studies have revealed that the anti‐HIV‐1 antib...

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Veröffentlicht in:FEBS Lett
Hauptverfasser: Puchol Tarazona, Alejandro A., Maresch, Daniel, Grill, Annette, Bakalarz, Janet, Torres Acosta, Juan A., Castilho, Alexandra, Steinkellner, Herta, Mach, Lukas
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Research Letters
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221030/
https://ncbi.nlm.nih.gov/pubmed/33263189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.14014
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