Sirt1 rescues the obesity induced by insulin-resistant constitutively-nuclear FoxO1 in POMC neurons of male mice

OBJECTIVE: The hypothalamus is the brain center that controls the energy balance. Anorexigenic proopiomelanocortin (POMC) neurons and orexigenic AgRP neurons in the arcuate nucleus of the hypothalamus plays critical roles in energy balance regulation. FoxO1 is a transcription factor regulated by ins...

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Vydáno v:Obesity (Silver Spring)
Hlavní autoři: Susanti, Vina Yanti, Sasaki, Tsutomu, Yokota-Hashimoto, Hiromi, Matsui, Sho, Lee, Yong-Soo, Kikuchi, Osamu, Shimpuku, Mayumi, Kim, Hye-Jin, Kobayashi, Masaki, Kitamura, Tadahiro
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
Brief Cutting Edge Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265245/
https://ncbi.nlm.nih.gov/pubmed/25044690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.20838
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