Sirt1 rescues the obesity induced by insulin-resistant constitutively-nuclear FoxO1 in POMC neurons of male mice

OBJECTIVE: The hypothalamus is the brain center that controls the energy balance. Anorexigenic proopiomelanocortin (POMC) neurons and orexigenic AgRP neurons in the arcuate nucleus of the hypothalamus plays critical roles in energy balance regulation. FoxO1 is a transcription factor regulated by ins...

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Dades bibliogràfiques
Publicat a:Obesity (Silver Spring)
Autors principals: Susanti, Vina Yanti, Sasaki, Tsutomu, Yokota-Hashimoto, Hiromi, Matsui, Sho, Lee, Yong-Soo, Kikuchi, Osamu, Shimpuku, Mayumi, Kim, Hye-Jin, Kobayashi, Masaki, Kitamura, Tadahiro
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
Matèries:
Brief Cutting Edge Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265245/
https://ncbi.nlm.nih.gov/pubmed/25044690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.20838
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