Hepatic FoxO1 Integrates Glucose Utilization and Lipid Synthesis through Regulation of Chrebp O-Glycosylation

In liver, glucose utilization and lipid synthesis are inextricably intertwined. When glucose availability exceeds its utilization, lipogenesis increases, leading to increased intrahepatic lipid content and lipoprotein secretion. Although the fate of three-carbon metabolites is largely determined by...

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Main Authors: Ido-Kitamura, Yukari, Sasaki, Tsutomu, Kobayashi, Masaki, Kim, Hye-Jin, Lee, Yong-Soo, Kikuchi, Osamu, Yokota-Hashimoto, Hiromi, Iizuka, Katsumi, Accili, Domenico, Kitamura, Tadahiro
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466224/
https://ncbi.nlm.nih.gov/pubmed/23056614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047231
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